Publikationen 2017

Sören Reinhard, Wei Zhang, and Ernst Wagner
Optimized Solid-Phase-Assisted Synthesis of Oleic Acid Containing siRNA Nanocarriers
ChemMedChem 12, 1464 – 1470 (2017)
doi: 10.1002/cmdc.201700350

Stephan Morys, Sarah Urnauer, Christine Spitzweg, and Ernst Wagner
EGFR Targeting and Shielding of pDNA Lipopolyplexes via Bivalent Attachment of a Sequence-Defined PEG Agent
Macromol. Biosci. 2017, 1700203
doi: 10.1002/mabi.201700203

Ana Krhac Levacic, Stephan Morys, Susanne Kempter, Ulrich Lächelt, and Ernst Wagner
Minicircle Versus Plasmid DNA Delivery by Receptor-Targeted Polyplexes
Human Gene Ther. 28 (10), (2017)
doi: 10.1089/hum.2017.123

Philipp Heller, Dominika Hobernik, Ulrich Lächelt, Meike Schinnerer, Benjamin Weber, Manfred Schmidt, Ernst Wagner, Matthias Bros, and Matthias Barz
Combining reactive triblock copolymers with functional crosslinkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines
J. Control. Release 258, 146-160 (2017).
doi: 10.1016/j.jconrel.2017.05.012

M. Kokkinopoulou, J. Simon, K. Landfester, V. Mailänder, I. Lieberwirth
Visualization of the protein corona: towards a biomolecular understanding of nanoparticle cell- interactions
Nanoscale 9, 8858-8870 (2017)

C.W. He, M. Parowatkin, V. Mailander, M. Flechtner-Mors, U. Ziener, K. Landfester, D. Crespy
Sequence-Controlled Delivery of Peptides from Hierarchically Structured Nanomaterials
ACS Appl. Mater. Interf., 9, 3885-3894 (2017)

J. Müller, K.N. Bauer, D. Prozeller, J. Simon, V. Mailander, F.R.  Wurm, S. Winzen, K. Landfester
Coating nanoparticles with tunable surfactants facilitates control over the protein corona
Biomaterials 115, 1-8 (2017).

G. Settanni, J.J. Zhou, T.C. Suo, S. Schöttler, K. Landfester, F. Schmid, V. Mailänder
Protein corona composition of poly(ethylene glycol)- and poly(phosphoester)-coated nanoparticles correlates strongly with the amino acid composition of the protein surface
Nanoscale 9, 2138-2144 (2017).

A.C. Bijlard, S. Wald, D. Crespy, A. Taden, F.R. Wurm, K. Landfester
Functional Colloidal Stabilization
Advanced Material Interfaces 4, 1600443 (2017)

I. Schlegel, R. Munoz-Espi, I. Lieberwirth, G. Floudas, Y. Suzuki, D. Crespy, K. LandfesterCrystallinity Tunes Permeability of Polymer Nanocapsules
Macromolecules 50, 4725-4732 (2017)

J. Herzberger, D. Leibig, J. Langhanki, C. Moers, T. Opatz, H. Frey,
“Clickable PEG” via anionic copolymerization of ethylene oxide and glycidyl propargyl ether
Polym. Chem. 2017, 8, 1882–1887

Hellmuth, I., Freund, I., Schlöder, J., Seidu-Larry, S., Thüring, K., Slama, K., Langhanki, J., Kaloyanova, S., Eigenbrod, T., Krumb, M., Röhm, S., Peneva K., Opatz, T., Jonuleit, H., Dalpke, A.H., Helm, M.,
Bioconjugation of Small Molecules to RNA Impedes Its Recognition by Toll-Like Receptor, (2017), 7. Fronti. Immunol., Mar. 24, 8:312,

Weber, B., Kappel, C., Scherer, M., Helm, M., Bros. M., Grabbe, S., Barz, M.,
PeptoSomes for Vaccination: Combining Antigen and Adjuvant in Polypept(o)ide-Based Polymersomes., (2017), Macromol Biosci., Jul. 31, Epub ahead of print

G. Settanni, J. Zhou, T. Suo, S. Schöttler, K. Landfester, F. Schmid, V. Mailänder,
Protein corona composition of PEGylated nanoparticles correlates strongly with amino acid composition of protein surface
Nanoscale 9, 2138 (2017).
doi:10.1039/C6NR07022A

P. Heller, B. Weber, J. Zhou, D. Hobernik, M. Bros, F. Schmid, M. Barz,
The influence of block ionomer microstructure on polyplex properties: Can simulations help to understand differences in transfection efficiency?
Small 13, 1603694 (2017).
doi:10.1002/smll.201603694

Daniel Gündel, Mareli Allmeroth,  Sarah Reime, Rudolf Zentel, Oliver Thews
Endocytotic uptake of HPMA-based polymers by different cancer cells: impact of extracellular acidosis and hypoxia
International Journal of Nanomedicine 12, 5571–5584 (2017),
http://dx.doi.org/10.2147/IJN.S136952

Sadaf Hanif, Bernd Oschmann, Dmitri Spetter, Muhammad Nawaz Tahir, Wolfgang Tremel and Rudolf Zentel*
Block copolymers from ionic liquids for the preparation of thin carbonaceous shells
Beilstein J. Org. Chem. 13, 1693-1701 (2917),
doi:10.3762/bjoc.13.163

Matthias Bartneck1§, Christopher Thorsten Schlößer1§, Matthias Barz2, Rudolf Zentel2, Christian Trautwein1, Twan Lammers3, Frank Tacke1*
Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers
ACS Nano (2017);
DOI: 10.1021/acsnano.7b04630

Tanja Weil, Matthias Barz, From Polymers to Functional Biomaterials, Macromolecular Bioscience 17 (10), (2017)
Olga Schäfer, Kristina Klinker, Lydia Braun, David Huesmann, Jennifer Schultze, Kaloian Koynov, and Matthias Barz
Combining Orthogonal Reactive Groups in Block Copolymers for Functional Nanoparticle Synthesis in a Single Step
ACS Macro Lett, (2017)
DOI: 10.1021/acsmacrolett.7b00678

Benjamin Weber, Cinja Kappel, Martin Scherer, Mark Helm, Matthias Bros, Stephan Grabbe, Matthias Barz
PeptoSomes for Vaccination: Combining Antigen and Adjuvant in Polypept(o)ide-Based Polymersomes
Macromol. Biosci. ,1700061 (2017)
DOI: 10.1002/mabi.201700061

M Bartneck, CT Schlößer, M Barz, R Zentel, C Trautwein, T Lammers, F Tacke, Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers, ACS Nano, 2017, 11 (10), pp 9689–9700.
DOI: 10.1021/acsnano.7b04630

Philipp Heller, Dominika Hobernik, Ulrich Lächelt, Meike Schinnerer, Benjamin Weber, Manfred Schmidt, Ernst Wagner, Matthias Bros, Matthias Barz
Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines
Journal of Controlled Release 258, 146–160 (2017)
DOI: 10.1016/j.jconrel.2017.05.012

Kristina Klinker ,Olga Schäfer, David Huesmann, Tobias Bauer, Leon Capelôa, Lydia Braun, Natascha Stergiou, Meike Schinnerer, Anjaneyulu Dirisala, Kanjiro Miyata, Kensuke Osada, Horacio Cabral, Kazunori Kataoka, Matthias Barz
Secondary-Structure-Driven Self-Assembly of Reactive Polypept(o)ides: Controlling Size,Shape,and Function of Core Cross-Linked Nanostructures
Angew. Chem. Int. Ed. 56, 9608–9613 (2017)
DOI: 10.1002/anie.201702624
Sekundärstrukturbildung als Triebkraft für die Selbstorganisation reaktiver Polypept(o)ide: Steuerung von Größe, Form und Funktion kernvernetzter Nanostrukturen
Angew. Chem. 129, 9737–9742 (2017)
DOI: 10.1002/ange.201702624

Y Tsvetkova, N Beztsinna, M Baues, D Klein, A Rix, SK Golombek, Wa’el Al Rawashdeh, Felix Gremse, Matthias Barz, Kaloian Koynov, Srinivas Banala, Wiltrud Lederle, Twan Lammers, Fabian Kiessling. Balancing Passive and Active Targeting to Different Tumor Compartments Using Riboflavin-Functionalized Polymeric Nanocarriers,
Nano Letters 17 (8), 4665-4674 (2017)
DOI: 10.1021/acs.nanolett.7b01171

Philipp Heller, Jiajia Zhou, Benjamin Weber, Dominika Hobernik, Matthias Bros, Friederike Schmid, Matthias Barz
Influence of Block Ionomer Microstructure on Polyplex Properties: Can Simulations Help to Understand Differences in Transfection Efficiency?
Small 13, 1603694 (2017)
DOI: 10.1002/smll.201603694

Regina Holm, Benjamin Weber, Philipp Heller, Kristina Klinker, Dana Westmeier, Dominic Docter, Roland H. Stauber, Matthias Barz
Synthesis and Characterization of Stimuli-Responsive Star-Like Polypept(o)ides: Introducing Biodegradable PeptoStars
Macromol. Biosci. 17, 1600514 (2017)
DOI: 10.1002/mabi.201600514

Ysasi, Alexandra B; Wagner, Willi L; Valenzuela, Cristian D; Kienzle, Arne; Servais, Andrew B; Bennett, Robert D; Tsuda, Akira; Ackermann, Maximilian; Mentzer, Steven J.
Evidence for pleural epithelial-mesenchymal transition in murine compensatory lung growth
PLoS One. 12(5), e0177921 (2017); DOI: 10.1371/journal.pone.0177921

Servais, Andrew; Kienzle, Arne; Valenzuela, Cristian D; Ysasi, Alexandra B; Wagner, Willi L; Tsuda, Akira; Ackermann, Maximilian; Mentzer, Steven J.
Tissue Engineering Part A. in press (2017); DOI: https://doi.org/10.1089/ten.tea.2017.0042

Kienzle, Arne; Kurch, Sven; Schlöder, Janine; Berges, Carsten; Ose, Robert; Schupp, Jonathan; Tuettenberg, Andrea; Weiss, Henning; Schultze, Jennifer; Winzen, Svenja; Schinnerer, Meike; Koynov, Kaloian; Mezger, Markus; Haass, Nikolas K; Tremel, Wolfgang; Jonuleit, Helmut.
Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-alpha
Advanced Healthcare Materials. 6(13), 2192-2659 (2017); doi: 10.1002/adhm.201700012

Yoanna Tsvetkova, Nataliia Beztsinna, Maike Baues, Dionne Klein, Anne Rix,
Susanne K. Golombek, Wa’el Al Rawashdeh, Felix Gremse, Matthias Barz, Kaloian Koynov,
Srinivas Banala, Wiltrud Lederle, Twan Lammers, and Fabian Kiessling
Balancing Passive and Active Targeting to Different Tumor Compartments Using Riboflavin-Functionalized  Polymeric Nanocarriers
Nano Lett. 17, 4665-4674 (2017)
doi: 10.1021/acs.nanolett.7b01171

Nadine Leber,+ Leonard Kaps,+ Misbah Aslam, Jonathan Schupp, Alexander Brose, David Schäffel, Karl Fischer, Mustafa Diken, Dennis Strand, Kaloian Koynov, Andrea Tuettenberg, Lutz Nuhn,* Rudolf Zentel,* Detlef Schuppan*
SiRNA-mediated In Vivo Gene Knockdown by Acid-Degradable Cationic Nanohydrogel Particles
J. Controlled Release 248, 10–23 (2017)
doi: 10.1016/j.jconrel.2016.12.006

Kai E. Moog, Matthias Barz, Matthias Bartneck, Figen Beceren-Braun, Nicole Mohr, Zhuojun Wu, Lydia Braun, Jens Dernedde, Elisa A. Liehn, Frank Tacke, Twan Lammers, Horst Kunz, Rudolf Zentel
Polymeric Selectin Ligands Mimicking Complex Carbohydrates: From Selectin Binders to Modifiers of Macrophage Migration
Angew. Chem. Int. Ed. 56 (5), 1416–1421 (2017)
doi:10.1002/anie.201610395
Polymere Selectinliganden als komplexe Glykomimetika: von Selectinbindung bis zur Modifizierung der Makrophagenmigration
Angew. Chem. 129 (5), 1438–1443 (2017)
doi:10.1002/ange.201610395

Can Ergen, Felix Heymann, Wa'el Al Rawashdeh, Felix Gremse, Matthias Bartneck, Ulf Panzer, Robert Pola, Michal Pechar, Gert Storm, Nicole Mohr, Matthias Barz, Rudolf Zentel, Fabian Kiessling, Christian Trautwein, Twan Lammers*, Frank Tacke*
Targeting distinct myeloid cell populations in vivo using polymers, liposomes and microbubbles
Biomaterials 114, 106–120 (2017)
doi:10.1016/j.biomaterials.2016.11.009