Publikationen 2012-2013

S. Trojandt, D. Knies, S. Pektor, S. Ritz, V. Mailänder, S. Grabbe, A. B. Reske-Kunz, M. Bros
"The chemotherapeutic agent topotecan differentially modulates the phenotype and function of dendritic cells"
Cancer Immunol Immunother 2013, 62, 1315–1326; DOI 10.1007/s00262-013-1431-9

L. Shen, T. Higuchi, I. Tubbe, N. Voltz, M. Krummen, S. Pektor, E. Montermann, K. Rausch, M. Schmidt, H. Schild, S. Grabbe, M. Bros
"A Trifunctional Dextran-Based Nanovaccine Targets and Activates Murine Dendritic Cells, and Induces Potent Cellular and Humoral Immune Responses In Vivo"
PLoS ONE 2013, 8, e80904; DOI:10.1371/journal.pone.0080904

N. Bacher, V. Raker, C. Hofmann, E. Graulich, M. Schwenk, R. Baumgrass, T. Bopp, U. Zechner, L. Merten, C. Becker *, K. Steinbrink *
"Interferon-α Suppresses cAMP to Disarm Human Regulatory T Cells."
Cancer Res. 2013, 73, 5647-56; DOI: 10.1158/0008-5472.CAN-12-3788

M. Barz, A. Duro-Castano, M.J. Vicent
"A versatile post-polymerization modification method for polyglutamic acid: synthesis of orthogonal reactive polyglutamates and their use in “click chemistry” "
Polymer Chemistry, 2013, 4, 2989-2994.

K. Landfester, V. Mailänder
"Nanocapsules with specific targeting and release properties using miniemulsion polymerization"
Expert Opin. Drug Deliv. 2013, 10, 593-609

D. Baumann, D. Hofmann, S. Nullmeier, P. Panther, C. Dietze, A. Musyanovych, S. Ritz, K. Landfester, V. Mailänder
"Complex encounters: nanoparticles in whole blood and their uptake into different types of white blood cells"
Nanomedicine: Nanotechnology, Biology, and Medicine 2013, 8, 699-713

S. Lerch, M. Dass, A. Musyanovych, K. Landfester, V. Mailänder
"Polymeric nanoparticles of different sizes overcome the cell membrane"
Eur. J. of Pharmaceutics and Biopharmaceutics 2013, 84, 265-274

H. Freichels, M. Wagner, P. Okwieka, R.G. Meyer, V. Mailänder, K. Landfester, A. Musyanovych
"(Oligo)mannose functionalized hydroxyethyl starch nanocapsules: en route to drug delivery systems with targeting properties"
J. Mater. Chem. B 2013, 1, 4338-4348

S. Tenzer, D. Docter, J. Kuharev, A. Musyanovych, V. Fetz, R. Hecht, F. Schlenk, D. Fischer, K. Kiouptsi, C. Reinhardt, K. Landfester, H.J. Schild, M. Maskos, S. Knauer, R. Stauber
"Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology"
Nature Nanotechnology 2013, 8, 772 – 781

M. Fichter, G. Baier, M. Dedters, L. Pretsch, A. Pietrzak-Nguyen, K. Landfester, S. Gehring
"Nanocapsules generated out of a polymeric dexamethasone shell suppress the inflammatory response of liver macrophages"
Nanomedicine: Nanotechnology, Biology and Medicine, 2013, 9, 1223-1234

A. Höcherl, K. Landfester, V. Mailänder
"Absolute Quantitation of Sub-Micrometer Particles in Cells by Flow Cytometrya"
Macromol. Biosci. 2013, 13, 1568-1575

Kristof Tappertzhofen, Verena V. Metz, Mario Hubo, Matthias Barz, Rolf Postina, Helmut Jonuleit, Rudolf Zentel*
"Synthesis of Maleimide-Functionalyzed HPMA- Copolymers and in vitro Characterization of the aRAGE- and Human Immunoglobulin" (huIgG)–Polymer Conjugates"
Macromol. Biosci. 13, 203- 214 (2013), DOI: 10.1002/mabi.201200344

Lutz Nuhn, Christoph Schüll, Holger Frey* and Rudolf Zentel*
"Combining Ring-Opening Multibranching and RAFT Polymerization: Multifunctional Linear-Hyperbranched Block Copolymers via Hyperbranched Macro Chain Transfer Agents"
Macromolecules 46, 2892 -2904 (2013); DOI 10.1021/ma4002897

Mareli Allmeroth, Dorothea Moderegger, Daniel Gündel, Hans-Georg Buchholz, Nicole Mohr, Kaloian Koynov, Frank Rösch, Oliver Thews, Rudolf Zentel*
"PEGylation of HPMA-based block copolymers enhances tumor accumulation in vivo: A quantitative study using radiolabeling and Positron Emission Tomography"
J. Controlled Release 172, 77 -85 (2013); DOI 10.1016/j.jconrel.2013.07.027

Mareli Allmeroth, Dorothea Moderegger, Daniel Gündel, Kaloian Koynov, Hans-Georg Buchholz, Kristin Rausch, Frank Rösch, Rudolf Zentel, Oliver Thews *
"HPMA-LMA copolymer drug carriers in oncology: An in vivo PET study to assess the tumor line-specific polymer uptake and body distribution"
Biomacromolecules 14, 3091–3101 (2013); Doi 10.1021/bm400709z

Lutz Nuhn, Sebastian Hartmann, Bjçrn Palitzsch, Bastian Gerlitzki, Edgar Schmitt, Rudolf Zentel,* and Horst Kunz*
"Water-Soluble Polymers Coupled with Glycopeptide Antigens and T-Cell Epitopes as Potential Antitumor Vaccines"
Angew. Chem. Int. Ed. 52, 10652 –10656 (2013)

Mirjam Hemmelmann, Kristin Mohr, Karl Fischer, Rudolf Zentel* and Manfred Schmidt*
"Interaction of pHPMA-pLMA copolymers with human blood serum and its components"
Mol. Pharmaceutics 10, 3769−3775 (2013); Doi 10.1021/mp400254b

Stefanie U. Frick, Nicole Bacher, Grit Baier, Volker Mailänder, Katharina Landfester, Kerstin Steinbrink*
"Functionalized Polystyrene Nanoparticles Trigger Human Dendritic Cell Maturation Resulting in Enhanced CD4+ T Cell Activation"
Macromol. Biosci. 2012, 12, 1637-1647; DOI: 10.1002/mabi.201200223